abstract：:Using the dimethylbenz(a)anthracene-induced mammary tumor model in rats, our studies indicated that there was a dose-response relationship between dietary selenium supplementation and the inhibition of mammary carcinogenesis. The degree of inhibition was proportional to the level of dietary selenium up to 5 ppm, at wh...

journal_title：Biological trace element research

authors： Ip C

更新日期：1983-08-01 00:00:00

abstract：:The influence of several commercial albumin preparations on the ferroxidase activity of ceruloplasmin (ferroxidase I, ferrous: O2 oxidoreductase EC 1.16.3.1) at pH 6.0 was determined using ferric-transferrin formation. The ability of several albumin preparations to inhibit the ferroxidase activity of ceruloplasmin dif...

journal_title：Biological trace element research

authors： Witwicki J,Chidambaram MV,Frieden E

更新日期：1983-04-01 00:00:00

abstract：:A review of the activity of metal compounds in mammalian cell transformation assays has been completed. Results from these assays appear to correlate well with the known carcinogenic activity displayed by specific metal compounds in vivo. Studies of cell transformation in vitro may provide information pertaining to th...

journal_title：Biological trace element research

authors： Daniel Heck J,Costa M

更新日期：1982-06-01 00:00:00

abstract：:Leukocytes incubated with Cu(II) showed a decrease in both glutathione reductase activity and reduced glutathione content. The glucose 6-phosphate dehydrogenase activity under the same conditions was not affected. Serum albumin added to mixtures prevented the loss of enzyme activity, whileD-penicillamine andL-histidin...

journal_title：Biological trace element research

authors： Rafter GW

更新日期：1982-06-01 00:00:00

abstract：:This study has analyzed the role of several serum constituents, that have been proposed to effect the following reactionin situ: {fx1-1} {fx1-2} These reactions were monitored by measuring the rate of Fe(II) oxidation in the presence of apo-transferrin (reaction A) and Fe(III)-transferrin formation (reaction B) at 465...

journal_title：Biological trace element research

authors： Carver FJ,Farb DL,Frieden E

更新日期：1982-03-01 00:00:00

abstract：:In three fully crossed, factorially arranged, completely randomized experiments, female weanling rats were fed a basal diet (containing about 10 ng of nickel and 2.3 μg of iron/g) supplemented with graded levels of nickel and iron. Iron was supplemented to the diet in experiment 1 at levels of 0, 25, 50, and 100 μg/g ...

journal_title：Biological trace element research

authors： Nielsen FH,Shuler TR

更新日期：1981-09-01 00:00:00

abstract：:A multitude of methods exists at present for the solubilization of biological tissues for atomic absorption analysis. We have examined several common methods of wet ashing using NBS bovine liver in order to determine which acids, acid combinations, or bases should be used as digesting agents for accurate and precise m...

journal_title：Biological trace element research

authors： Clegg MS,Keen CL,Lönnerdal B,Hurley LS

更新日期：1981-06-01 00:00:00

abstract：:Forty-six elements have been detected in fresh banana pulp purchased weekly in Pittsburgh, PA for the past twelve years (1968-1980). Samples were prepared by lyophilization or low temperature ashing. Analyses were performed using X-ray fluorescence spectrometry, optical emission spectrometry, atomic absorption spectro...

journal_title：Biological trace element research

authors： Cowgill UM

更新日期：1981-03-01 00:00:00

abstract：:Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common tr...

journal_title：Biological trace element research

authors： Huang PC,Smith B,Bohdan P,Corrigan A

更新日期：1980-09-01 00:00:00

abstract：:The incorporation of(3)H-thymidine into DNA in the brains of the 17-day and 20-day old rat fetuses was significantly reduced by maternal zinc restriction during pregnancy. The activity of the enzyme thymidine kinase (EC 2.7.1.21) was similarly reduced in the zine-deprived fetal brains on days 14 and 20 of gestation, b...

journal_title：Biological trace element research

authors： Dreosti IE,Record IR,Manuel SJ

更新日期：1980-03-01 00:00:00

abstract：:It has become evident over the last two decades that there is an intimate relationship between the trace elements and cancer. Some trace elements have been shown to be carcinogens, others appear to provide protection against cancer. Profound changes in trace element concentrations and distribution occur in patients wi...

journal_title：Biological trace element research

authors： Pories WJ,van Rij AM,Mansour EG,Flynn A

更新日期：1979-08-01 00:00:00

abstract：:Studies were designed to characterize the plasma membrane polypeptide composition of normal rat kidney (NRK) and virus-transformed NRK cells as a function of time following iron deprivation. Using this approach we found that rapid depletion of iron from the cells increases the amounts of two membrane-associated glycop...

journal_title：Biological trace element research

authors： Fernandez-Pol JA

更新日期：1979-06-01 00:00:00

abstract：:A cohort study on platers in Tokyo was carried out using the records of the Tokyo Health Insurance Society of Plating Industry. The type of work and chromium-exposure history of each member of this society was investigated by a questionnaire sent to the manager of each factory. The recovery rate of the questionnaire w...

journal_title：Biological trace element research

authors： Okubo T,Tsuchiya K

更新日期：1979-03-01 00:00:00